The compact Thermo Scientific NanoDrop Eight Spectrophotometer measures eight samples at a time in less than 20 seconds. It is an ideal choice for pharma/biotech and academic researchers needing a higher throughput capacity for measuring nucleic acid and protein samples, enables purity and concentration assessments. Built-in Acclaro Sample Intelligence technology helps identify and correct for the contaminants present. Make informed decisions on sample quality and improve your success in downstream applications with NanoDrop technology.
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NanoDrop Eight spectrophotometers features
- Requires only 1–2 µL of sample without dilution, even for highly concentrated samples, 8 pedestal array for measurements of up to 8 samples in 20 seconds
- Ergonomic ambidextrous pipetting – Pedestal array is aligned perpendicular to the front of the instrument creating a natural pipetting motion for users; the pipette guide is magnetic and movable from side-to-side allowing left- and righthanded users to quickly and comfortably dispense samples
- Simply pipet a drop of your DNA, RNA, or protein sample on the pedestal and pull down the arm;
- Results appear in seconds of initiating a measurement, and Auto-Blank and Auto-Measure settings can further streamline your workflow
- Measure up to 10000 ng/µL dsDNA or 145 mg/mL IgG without dilution
DNA, RNA, and protein quantification, full spectral data, purity ratios (A260/A280, A260/A230), and more - Measure the full UV-Vis spectrum from 190–850 nm, allowing a range of assays as dsDNA, RNA, Protein A280, and UV-Vis
Acclaro Sample Intelligence Technology
Thermo Scientific Acclaro Sample Intelligence Technology software analyzes absorbance across the whole UV-Vis spectrum, not just wavelengths specific to nucleic acids and proteins. Acclaro Sample Intelligence technology gives customers confidence in their sample by running blank assessment, warning when a purity ratio is out of tolerance, and identificying sample contaminants in dsDNA, RNA, and Protein A280. Differentiates between mammalian dsDNA and RNA within the dsDNA and RNA applications. It then applies powerful chemometric algorithms to identify contaminants in your samples and correct quantitation results. You get more reliable downstream assay results and avoid potential rework with this efficient, breakthrough capability.
Stand-alone instrument with local control
- Auto-blank and auto-measure option, Autoranging pedestal pathlengths for measuring undiluted samples
- 8 pedestal array for measurements of up to 8 samples in 20 seconds
- Sample volume: 1.0 – 2.0 microliter
- Detection Limits: dsDNA: 2.0 ng/µL; IgG: 0.03 mg/mL
- Maximum Concentration: dsDNA: 10000 ng/μL, IgG: 145 mg/mL
- Measurement and Data Processing Time: 8 samples ≤ 20 sec
- Measurement Repeatability*** 0.002 A/cm or 1% CV, whichever is greater
- Wavelength Range: 190–850 nm
- Wavelength Accuracy ±1 nm
- Absorbance Range (10 mm equivalent): 0.04–200 Abs
- Absorbance Accuracy: 3% at 0.97A, 302 nm, 23 ± 2C°
- Spectral Resolution: ≤1.8 nm (FWHM at Hg 254 nm)
- Pathlength: 1.0 mm, 0.2 mm, 0.1 mm (auto adjusting)
- Light Source: Xenon flash lamp
- Detector Type: 2048-element CMOS linear image sensor
- Dimensions: 24 x 33 x 17 cm (9.4 x 13 x 6.7 in) (LxWxH)
- Weight: 3.7 kg (8.2 lb)
- Electrical Requirements: 100/240 V
- Power Consumption: 3W at Idle; 15W at Working Conditions
Acclaro™ Sample Intelligence technology
- Know the true concentration of your nucleic acid or protein without the interfering effects of sample contaminants. Understanding your sample composition helps downstream experiments go right the first time.
- Contaminant identification – recognizes common contaminants in nucleic acid and protein samples that could inhibit downstream reactions or falsely elevate calculated concentrations.
- Corrected calculations – applies chemometric algorithms to determine the true concentration of your analyte without the contaminant.
- Differentiate DNA from RNA – algorithms can identify mammalian RNA contaminating a dsDNA sample or mammalian dsDNA contaminating an RNA sample.
Streamline management – SciVault Software integrates into NanoDrop Eight Software user interface
- Comply with US FDA 21 CFR Part 11 Regulation – Control user account access, apply digital signatures, and review audit logs
- Network multiple instruments – Install SciVault Software on a central computer to control privileges and view audit logs across multiple NanoDrop Eight Instruments in different labs
- Optional Thermo Scientific™ SciVault™ Software helps your lab stay compliant with US FDA data regulations every step of the way.
- Validate your systems – IQ/OQ documents and services available to confirm your instrument is running within manufacturer’s specifications
- NanoDrop Eight spectrophotometer enhancements
- Automated exports for LIMS – set a directory for data to be automatically exported; have your LIMS software sweep the folder to pull in NanoDrop Eight instrument data for archiving
