The Innovator Blog Series celebrates research conducted by 10x Genomics customers who have demonstrated scientific ingen...
Cancer is a multifaceted disease driven by the complex interplay of diverse immune cells. To elucidate the heterogeneity of tumor microenvironments and assess the efficacy of innovative therapeutics, leveraging Chromium Single Cell Multiome ATAC + Gene Expression for comprehensive epigenetic profiling is essential. This advanced technique is pivotal in deciphering the mechanisms of gene activation and silencing that propel cancer progression.
10x Genomics has made a scientific breakthrough to resolve limitations of former methods when they introduced BEAM (Barcode Enabled Antigen Mapping).
Chromium Single Cell Immune profiling allows simultaneous analysis of T-cell receptor (TCR) sequences and gene expression profiles from the same individual cells, enabling researchers to measure clonal expansion and identify often overlooked immune cells in the tumor microenvironment.
Hematopoietic and pluripotent stem cells (HPSCs) mobilization is critical for effective autologous stem cell transplants...
Recent advancements have utilized the Chromium Single Cell Immune Profiling assay to develop an in-depth tumor microenvironment atlas, focusing on primary tumors, metastases, and particularly ascites – the fluid accumulation common in advanced cases. This study identified immune cells in ascites that could potentially enhance the immune response against primary and metastatic tumors.
